He was born in Lahore to a Sodhi family of Khatri clan. His father was Hari Das and mother Anup Devi, and his name was Jetha, 'first born'. His wife was Bibi Bhani, the younger daughter of Guru Amar Das, the third guru of the Sikhs. They had three sons: Prithi Chand, Mahadev and Arjan Dev.

As a Guru One of his main contributions to Sikhism was organizing the structure of Sikh society. Additionally, he was the author of Laava, the hymns of the Marriage Rites, the designer of the Harmandir Sahib, and the planner and creator of the township of Ramdaspur (later Amritsar).

A hymn by Guru Ram Das from page 305 of the Guru Granth Sahib: